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Inside of a review in breast cancer cells, The mix of lapatinib, a dual HER2/neu and EGFR tyrosine kinase inhibitor, with INK128 prevented both equally HER2 and HER3 phosphorylation induced by INK128 and made synergistic induction of mobile death in several HER2-positive cell lines proof against trastuzumab and lapatinib. In vivoLicorineEven so, ce